This test detects all species within the Borrelia genus. This genus includes Lyme bacteria (Borrelia burgdorferi and other related species) and Borrelia miyamotoi (causative agent of Hard tick relapsing fever)

Borrelia burgdorferi is a spiral-shaped bacteria that is the most common cause of Lyme disease. Lyme disease occurs more often in dogs than cats. Horses are also often infected with B. burgdorferi. Common symptoms across most mammals consists of lameness, stiffness, loss of appetite, fatigue and/or difficulty breathing.

Anaplasma phagocytophilum, a bacteria, that often causes lethargy, elevated body temperature, and appetite loss. This infection has been documented in dogs, cat, horses and other mammals.

This protozoan can cause a range of symptoms across various mammal species. Infection is characterized by fever, reduced food intake, weight loss, anemia, and thrombocytopenia. Symptoms vary across domestic species. This protozoan is known to parasitize dogs, cats, pigs, sheep, goats, cattle, and horses.

This bacteria causes tularemia, a disease that causes increased pulse and respiratory rate, coughing diarrhea, oral ulceration, pollakiuria with lymphadenopathy, and hepatosplenomegaly. The presentation of tularemia varies across domestic species and has been reported in sheep, cats, dogs, and horses.

This bacteria causes Rocky Mountain Spotted Fever. This disease primarily affects dogs and is very rare in cats. Symptoms of infection include fever, anorexia, lymphadenopathy, polyarthritis, coughing, abdominal pain, vomiting, diarrhea, and edema of the face or extremities.

E. chaffeensis is an obligate, intracellular bacteria that causes Ehrlichiosis. This bacteria primarily attacks cells of the immune system. Symptoms include fever, swollen lymph nodes, depression, weight loss, vomiting, and diarrhea. Chronic ehrlichiosis can be severe and cause organ failure. Documented hosts are dogs, cats, cattle, sheep goats, rodents, and deer.

E. canis is an obligate, intracellular bacteria that primarily infects dogs. This bacteria causes Ehrlichiosis and primarily attacks cells of the immune system. Symptoms include fever, swollen lymph nodes, depression, weight loss, vomiting, and diarrhea. Chronic ehrlichiosis can be severe and cause organ failure. Other hosts may include cattle, sheep, goats, rodents, and deer.

E. ewingii is an obligate, intracellular bacteria that causes Ehrlichiosis. This bacteria primarily attacks cells of the immune system. Symptoms can include anorexia, fever, epistaxis, hemorrhage, and sometimes results in death. This bacteria primarily causes disease in dogs.

Several species of Bartonella are pathogenic to animals. It is primarily found to be disease-causing in cats and dogs. Cats are primarily asymptomatic carriers of Bartonella henselae. Dogs can present with varied symptoms that include fever, endocarditis and myocarditis, granulomatous lymphadenitis, cardiac arrhythmias, granulomatous rhinitis, and epistaxis.